8QMS

Succinic semialdehyde dehydrogenase from E. coli with Q262R substitution and bound NAD+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004030	molecular_function	aldehyde dehydrogenase [NAD(P)+] activity
A	0004777	molecular_function	succinate-semialdehyde dehydrogenase (NAD+) activity
A	0006099	biological_process	tricarboxylic acid cycle
A	0006527	biological_process	L-arginine catabolic process
A	0009013	molecular_function	succinate-semialdehyde dehydrogenase [NAD(P)+] activity
A	0009447	biological_process	putrescine catabolic process
A	0009450	biological_process	gamma-aminobutyric acid catabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
A	0036243	molecular_function	succinate-semialdehyde dehydrogenase (NADP+) activity
A	0042803	molecular_function	protein homodimerization activity
A	0070458	biological_process	cellular detoxification of nitrogen compound
B	0004030	molecular_function	aldehyde dehydrogenase [NAD(P)+] activity
B	0004777	molecular_function	succinate-semialdehyde dehydrogenase (NAD+) activity
B	0006099	biological_process	tricarboxylic acid cycle
B	0006527	biological_process	L-arginine catabolic process
B	0009013	molecular_function	succinate-semialdehyde dehydrogenase [NAD(P)+] activity
B	0009447	biological_process	putrescine catabolic process
B	0009450	biological_process	gamma-aminobutyric acid catabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
B	0036243	molecular_function	succinate-semialdehyde dehydrogenase (NADP+) activity
B	0042803	molecular_function	protein homodimerization activity
B	0070458	biological_process	cellular detoxification of nitrogen compound
C	0004030	molecular_function	aldehyde dehydrogenase [NAD(P)+] activity
C	0004777	molecular_function	succinate-semialdehyde dehydrogenase (NAD+) activity
C	0006099	biological_process	tricarboxylic acid cycle
C	0006527	biological_process	L-arginine catabolic process
C	0009013	molecular_function	succinate-semialdehyde dehydrogenase [NAD(P)+] activity
C	0009447	biological_process	putrescine catabolic process
C	0009450	biological_process	gamma-aminobutyric acid catabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
C	0036243	molecular_function	succinate-semialdehyde dehydrogenase (NADP+) activity
C	0042803	molecular_function	protein homodimerization activity
C	0070458	biological_process	cellular detoxification of nitrogen compound
D	0004030	molecular_function	aldehyde dehydrogenase [NAD(P)+] activity
D	0004777	molecular_function	succinate-semialdehyde dehydrogenase (NAD+) activity
D	0006099	biological_process	tricarboxylic acid cycle
D	0006527	biological_process	L-arginine catabolic process
D	0009013	molecular_function	succinate-semialdehyde dehydrogenase [NAD(P)+] activity
D	0009447	biological_process	putrescine catabolic process
D	0009450	biological_process	gamma-aminobutyric acid catabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
D	0036243	molecular_function	succinate-semialdehyde dehydrogenase (NADP+) activity
D	0042803	molecular_function	protein homodimerization activity
D	0070458	biological_process	cellular detoxification of nitrogen compound

Functional Information from PROSITE/UniProt

site_id	PS00070
Number of Residues	12
Details	ALDEHYDE_DEHYDR_CYS Aldehyde dehydrogenases cysteine active site. YrNTGQVCAAAK

Chain	Residue	Details
A	TYR261-LYS272

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10008","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU10008","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	28
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P25526","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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