8QFZ
TSLP-Bicycle complex
Summary for 8QFZ
Entry DOI | 10.2210/pdb8qfz/pdb |
Descriptor | Thymic stromal lymphopoietin, CYS-HIS-TRP-LEU-GLU-ASN-CYS-TRP-ARG-GLY-PHE-CYS, 1-[3,5-bis(3-bromanylpropanoyl)-1,3,5-triazinan-1-yl]-3-bromanyl-propan-1-one, ... (4 entities in total) |
Functional Keywords | inhibitor, complex, hormone |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 16631.69 |
Authors | Petersen, J. (deposition date: 2023-09-05, release date: 2024-02-07, Last modification date: 2024-02-21) |
Primary citation | Narjes, F.,Edfeldt, F.,Petersen, J.,Oster, L.,Hamblet, C.,Bird, J.,Bold, P.,Rae, R.,Back, E.,Stomilovic, S.,Zlatoidsky, P.,Svensson, T.,Hidestal, L.,Kunalingam, L.,Shamovsky, I.,De Maria, L.,Gordon, E.,Lewis, R.J.,Watcham, S.,van Rietschoten, K.,Mudd, G.E.,Harrison, H.,Chen, L.,Skynner, M.J. Discovery and Characterization of a Bicyclic Peptide (Bicycle) Binder to Thymic Stromal Lymphopoietin. J.Med.Chem., 67:2220-2235, 2024 Cited by PubMed: 38284169DOI: 10.1021/acs.jmedchem.3c02163 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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