8QDV

Structure of 14-3-3 zeta delta C with the bivalent tau-pS214-pS324 peptide

Summary for 8QDV

• Entry DOI: 10.2210/pdb8qdv/pdb
• Descriptor: 14-3-3 protein zeta/delta, Microtubule-associated protein tau (3 entities in total)
• Functional Keywords: 14-3-3 zeta, tau, protein-protein interaction, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 112776.83

Authors

van den Oetelaar, M.C.M.,Brunsveld, L.,Ottmann, C. (deposition date: 2023-08-30, release date: 2024-09-11, Last modification date: 2024-09-18)

• Primary citation: Hochmair, J.,van den Oetelaar, M.C.M.,Ravatt, R.,Lemmens, L.J.M.,Ponce, R.,Semenova, E.,Mohapatra, S.,Ottmann, C.,Diez, L.,Brunsveld, L.,Wegmann, S.; 14-3-3zeta binding increases cytosolic phospho-Tau solubility by decreasing its condensation, aggregation, and microtubule association; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)