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8Q7N

cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region)

Summary for 8Q7N
Entry DOI10.2210/pdb8q7n/pdb
EMDB information18225
DescriptorU5 snRNA, WW domain-binding protein 4, MINX pre-mRNA, ... (21 entities in total)
Functional Keywordsspliceosome, pre-catalytic spliceosome, spliceosomal b complex, splicing
Biological sourceHomo sapiens (human)
More
Total number of polymer chains21
Total formula weight1427478.54
Authors
Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Urlaub, H.,Stark, H.,Luehrmann, R. (deposition date: 2023-08-16, release date: 2024-01-24, Last modification date: 2024-08-07)
Primary citationZhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Urlaub, H.,Stark, H.,Luhrmann, R.
Cryo-EM analyses of dimerized spliceosomes provide new insights into the functions of B complex proteins.
Embo J., 43:1065-1088, 2024
Cited by
PubMed: 38383864
DOI: 10.1038/s44318-024-00052-1
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.1 Å)
Structure validation

224201

数据于2024-08-28公开中

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