8Q7N
cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region)
Summary for 8Q7N
Entry DOI | 10.2210/pdb8q7n/pdb |
EMDB information | 18225 |
Descriptor | U5 snRNA, WW domain-binding protein 4, MINX pre-mRNA, ... (21 entities in total) |
Functional Keywords | spliceosome, pre-catalytic spliceosome, spliceosomal b complex, splicing |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 21 |
Total formula weight | 1427478.54 |
Authors | Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Urlaub, H.,Stark, H.,Luehrmann, R. (deposition date: 2023-08-16, release date: 2024-01-24, Last modification date: 2024-08-07) |
Primary citation | Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Urlaub, H.,Stark, H.,Luhrmann, R. Cryo-EM analyses of dimerized spliceosomes provide new insights into the functions of B complex proteins. Embo J., 43:1065-1088, 2024 Cited by PubMed: 38383864DOI: 10.1038/s44318-024-00052-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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