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8Q6E

Aerobic crystal structure of HIF prolyl hydroxylase 2 (PHD2 181-407) in complex with Fe(III), 2-oxoglutarate (2OG) and HIF2alpha-CODD peptide

Summary for 8Q6E
Entry DOI10.2210/pdb8q6e/pdb
DescriptorEgl nine homolog 1, Endothelial PAS domain-containing protein 1, MAGNESIUM ION, ... (7 entities in total)
Functional Keywords2og oxygenases, oxygen sensor, jelly-roll, oxidoreductase
Biological sourceHomo sapiens (human)
More
Total number of polymer chains2
Total formula weight28691.89
Authors
Fiorini, G.,Figg Jr, W.D.,Schofield, C.J. (deposition date: 2023-08-11, release date: 2024-08-21)
Primary citationFiorini, G.,Figg Jr, W.D.,Schofield, C.J.
HIF prolyl hydroxylase 2 in complex with HIF2alpha-CODD
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.37 Å)
Structure validation

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PDB entries from 2024-12-18

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