8Q2G
X-ray structure of LysECD7 endolysin against Gram-negative bacteria
Summary for 8Q2G
Entry DOI | 10.2210/pdb8q2g/pdb |
Descriptor | Peptidoglycan L-alanyl-D-glutamate endopeptidase (2 entities in total) |
Functional Keywords | endolysins, bacteriophage lytic enzymes, gram-negative bacteria, antibacterial therapy, antimicrobial agents, antibiotic, antimicrobial protein |
Biological source | Escherichia phage ECD7 |
Total number of polymer chains | 1 |
Total formula weight | 16117.48 |
Authors | |
Primary citation | Vasina, D.V.,Antonova, N.P.,Gushchin, V.A.,Aleshkin, A.V.,Fursov, M.V.,Fursova, A.D.,Gancheva, P.G.,Grigoriev, I.V.,Grinkevich, P.,Kondratev, A.V.,Kostarnoy, A.V.,Lendel, A.M.,Makarov, V.V.,Nikiforova, M.A.,Pochtovyi, A.A.,Prudnikova, T.,Remizov, T.A.,Shevlyagina, N.V.,Siniavin, A.E.,Smirnova, N.S.,Terechov, A.A.,Tkachuk, A.P.,Usachev, E.V.,Vorobev, A.M.,Yakimakha, V.S.,Yudin, S.M.,Zackharova, A.A.,Zhukhovitsky, V.G.,Logunov, D.Y.,Gintsburg, A.L. Development of novel antimicrobials with engineered endolysin LysECD7-SMAP to combat Gram-negative bacterial infections J.Biomed.Sci., 31:75-, 2024 Cited by DOI: 10.1186/s12929-024-01065-yPDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.49 Å) |
Structure validation
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