8PXI

Crystal structure of Endothiapepsin soaked with FRG283

Summary for 8PXI

Entry DOI	10.2210/pdb8pxi/pdb
Descriptor	Endothiapepsin, (4S)-2-METHYL-2,4-PENTANEDIOL, DIMETHYL SULFOXIDE, ... (5 entities in total)
Functional Keywords	endothiapepsin, ligand complex, hydrolase
Biological source	Cryphonectria parasitica (chestnut blight fungus)
Total number of polymer chains	1
Total formula weight	34431.80
Authors	Mueller, J.M.,Eckelt, S.,Klebe, G.,Glinca, S. (deposition date: 2023-07-23, release date: 2024-08-07, Last modification date: 2026-01-14)
Primary citation	Huschmann, F.U.,Mueller, J.,Metz, A.,Ruf, M.,Senst, J.,Glinca, S.,Schiebel, J.,Heine, A.,Klebe, G. Screening, Growing, and Validation by Catalog: Using Synthetic Intermediates from Natural Product Libraries to Discover Fragments for an Aspartic Protease Through Crystallography Crystals, 14:755-, 2024 Cited by DOI: 10.3390/cryst14090755 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation