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8PPM

IL-12Rb1 neutralizing Fab4, crystal kappa variant

Summary for 8PPM
Entry DOI10.2210/pdb8ppm/pdb
Related8C7M 8ODX
DescriptorFab4 heavy chain, Fab4 Light chain, crystal kappa variant, POTASSIUM ION, ... (4 entities in total)
Functional Keywordsantibody, fab fragment, designed crystal contact, immunosuppressant
Biological sourceHomo sapiens x Mus musculus hybrid cell line
More
Total number of polymer chains2
Total formula weight48104.51
Authors
Bloch, Y.,Savvides, S.N. (deposition date: 2023-07-07, release date: 2024-02-07, Last modification date: 2024-05-01)
Primary citationBloch, Y.,Felix, J.,Merceron, R.,Provost, M.,Symakani, R.A.,De Backer, R.,Lambert, E.,Mehdipour, A.R.,Savvides, S.N.
Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31:591-597, 2024
Cited by
PubMed: 38287195
DOI: 10.1038/s41594-023-01190-6
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.03 Å)
Structure validation

221051

數據於2024-06-12公開中

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