8PMX

rat HEV P domain in complex with glycan-sensitive nAb p60.12

Summary for 8PMX

• Entry DOI: 10.2210/pdb8pmx/pdb
• Descriptor: Pro-secreted protein ORF2, Fab p60.12-HC, Fab p60.12-LC (3 entities in total)
• Functional Keywords: rat hev, p domain, non-glycosylated, glycan-sensitive, neutralizing antibody (nab), viral protein
• Biological source: Hepatitis E virus rat/R63/DEU/2009; More
• Total number of polymer chains: 4
• Total formula weight: 83725.76

Authors

Ssebyatika, G.,Krey, T. (deposition date: 2023-06-29, release date: 2024-07-10)

• Primary citation: Ssebyatika, G.,Dinkelborg, K.,Stroeh, L.J.,Hinte, F.,Corneillie, L.,Hueffner, L.,Guzman, E.M.,Nankya, P.L.,Plueckebaum, N.,Prallet, S.,Mehnert, A.K.,Verhoye, L.,Juergens, C.,Steinmann, E.,Wedemeyer, H.,Viejo-Borbolla, A.,Dao Thi, L.V.,Pietschmann, T.,Luetgehetmann, M.,Meuleman, P.,Dandri, M.,Krey, T.,Behrendt, P.; A novel class of broadly neutralizing hepatitis E virus-specific human antibodies; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.922 Å)