8PM3

Crystal structure of MAP2K6 with a covalent compound GCL94

8PM3 の概要

• エントリーDOI: 10.2210/pdb8pm3/pdb
• 分子名称: Dual specificity mitogen-activated protein kinase kinase 6, ~{N}-[3-(2-azanylpyridin-4-yl)phenyl]propanamide (3 entities in total)
• 機能のキーワード: kinase, covalent, inhibitor, map2k6, structural genomics, structural genomics consortium, sgc, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 131964.69

構造登録者

Wang, G.Q.,Seidler, N.,Roehm, S.,Gehringer, M.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2023-06-28, 公開日: 2023-09-20)

• 主引用文献: Wang, G.Q.,Seidler, N.,Roehm, S.,Gehringer, M.,Knapp, S.,Structural Genomics Consortium (SGC); Crystal structure of MAP2K6 with a covalent compound GCL94; To Be Published,

実験手法

X-RAY DIFFRACTION (2 Å)