8PC2
SelDeg51 in complex with FKBP51FK1 domain and pVHL:EloB:EloC
Summary for 8PC2
Entry DOI | 10.2210/pdb8pc2/pdb |
Descriptor | von Hippel-Lindau disease tumor suppressor, Elongin-C, Elongin-B, ... (6 entities in total) |
Functional Keywords | fkbp51, safit, complex, protac, isomerase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 113545.88 |
Authors | Meyners, C.,Walz, M.,Geiger, T.M.,Hausch, F. (deposition date: 2023-06-09, release date: 2023-11-15, Last modification date: 2024-01-24) |
Primary citation | Geiger, T.M.,Walz, M.,Meyners, C.,Kuehn, A.,Dreizler, J.K.,Sugiarto, W.O.,Maciel, E.V.S.,Zheng, M.,Lermyte, F.,Hausch, F. Discovery of a Potent Proteolysis Targeting Chimera Enables Targeting the Scaffolding Functions of FK506-Binding Protein 51 (FKBP51). Angew.Chem.Int.Ed.Engl., 63:e202309706-e202309706, 2024 Cited by PubMed: 37942685DOI: 10.1002/anie.202309706 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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