8PAW
Crystal structure of MST1 with a MAP4K1 SMOL inhibitor
Summary for 8PAW
| Entry DOI | 10.2210/pdb8paw/pdb |
| Descriptor | Serine/threonine-protein kinase 4 37kDa subunit, ASPARTIC ACID, 1-[3,5-bis(fluoranyl)-4-[[3-(1-propan-2-ylpyrazol-3-yl)-1~{H}-pyrrolo[2,3-b]pyridin-4-yl]oxy]phenyl]-3-(2-methoxyethyl)urea, ... (6 entities in total) |
| Functional Keywords | kinase, inhibitor, drug discovery, transferase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 72892.29 |
| Authors | |
| Primary citation | Friberg, A.,Mowat, J.,Offringa, R. Identification and optimization of Azaindole based MAP4K1 Inhibitors and the discovery of BAY-405 To Be Published, |
| Experimental method |
Structure validation
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