8P8E
Crystal structure of endolysin gp46 from Pseudomonas aeruginosa bacteriophage vB_PaeM_KTN6
This is a non-PDB format compatible entry.
Summary for 8P8E
| Entry DOI | 10.2210/pdb8p8e/pdb |
| Descriptor | Glycoside hydrolase family protein, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... (4 entities in total) |
| Functional Keywords | endolysin, phage lysozyme, muramidase, antimicrobial, hydrolase |
| Biological source | Bacteriophage sp. |
| Total number of polymer chains | 1 |
| Total formula weight | 24782.15 |
| Authors | van Raaij, M.J.,Sanz-Gaitero, M. (deposition date: 2023-06-01, release date: 2024-05-08, Last modification date: 2024-08-21) |
| Primary citation | Sanz-Gaitero, M.,De Maesschalck, V.,Patel, A.,Longin, H.,Van Noort, V.,Rodriguez-Rubio, L.,van Ryne, M.,Danis-Wlodarczyk, K.,Drulis-Kawa, Z.,Mesnage, S.,van Raaij, M.,Lavigne, R. Structural and Biochemical Characterization of a New Phage-Encoded Muramidase, KTN6 Gp46. Phage (New Rochelle), 5:53-62, 2024 Cited by PubMed Abstract: Endolysins are phage-encoded lytic enzymes that degrade bacterial peptidoglycan at the end of phage lytic cycles to release new phage particles. These enzymes are being explored as an alternative to small-molecule antibiotics. PubMed: 39119210DOI: 10.1089/phage.2023.0040 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.391 Å) |
Structure validation
Download full validation report
