8P7B

CryoEM structure of METTL6 tRNA SerRS complex in a 1:2:2 stoichiometry

Summary for 8P7B

• Entry DOI: 10.2210/pdb8p7b/pdb
• Related: 8OWX 8OWY
• EMDB information: 17528
• Descriptor: Serine--tRNA ligase, cytoplasmic, tRNA N(3)-methylcytidine methyltransferase METTL6, Serine tRNA, ... (7 entities in total)
• Functional Keywords: mettl6, trna, serrs, serine trna, 3-methylcytosine, rna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 206709.83

Authors

Throll, P.,Dolce, L.G.,Kowalinski, E. (deposition date: 2023-05-30, release date: 2024-06-12, Last modification date: 2024-07-10)

• Primary citation: Throll, P.,G Dolce, L.,Rico-Lastres, P.,Arnold, K.,Tengo, L.,Basu, S.,Kaiser, S.,Schneider, R.,Kowalinski, E.; Structural basis of tRNA recognition by the m 3 C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase.; Nat.Struct.Mol.Biol., 2024; PubMed: 38918637; DOI: 10.1038/s41594-024-01341-3

Experimental method

ELECTRON MICROSCOPY (2.42 Å)