8P7B
CryoEM structure of METTL6 tRNA SerRS complex in a 1:2:2 stoichiometry
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, D) | Serine--tRNA ligase, cytoplasmic | polymer | 514 | 58863.2 | 2 | UniProt (P49591) Pfam (PF02403) Pfam (PF00587) | Homo sapiens (human) | Seryl-tRNA synthetase,SerRS,Seryl-tRNA(Ser/Sec) synthetase |
| 2 | C (A) | tRNA N(3)-methylcytidine methyltransferase METTL6 | polymer | 284 | 33296.1 | 1 | UniProt (Q8TCB7) Pfam (PF08242) | Homo sapiens (human) | Methyltransferase-like protein 6,hMETTL6 |
| 3 | D (T) | Serine tRNA | polymer | 85 | 27536.5 | 1 | Trichoplusia ni | ||
| 4 | E (R) | Serine tRNA | polymer | 85 | 27620.6 | 1 | Trichoplusia ni | ||
| 5 | F (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 6 | G, H, I, J, K... (T, R) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 7 | M, N (T, R) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 206179.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 530.2 | |
| All* | Total formula weight | 206709.8 |
