8OWX
Crystal Structure of METTL6 bound to SAH
Summary for 8OWX
| Entry DOI | 10.2210/pdb8owx/pdb |
| Descriptor | tRNA N(3)-methylcytidine methyltransferase METTL6, S-ADENOSYL-L-HOMOCYSTEINE, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total) |
| Functional Keywords | trna modification, m3c, methyltransferase, rna binding protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 65744.95 |
| Authors | Throll, P.,Basu, S.,Dolce, L.G.,Kowalinski, E. (deposition date: 2023-04-28, release date: 2024-05-08, Last modification date: 2024-07-03) |
| Primary citation | Throll, P.,G.Dolce, L.,Rico-Lastres, P.,Arnold, K.,Tengo, L.,Basu, S.,Kaiser, S.,Schneider, R.,Kowalinski, E. Structural basis of tRNA recognition by the m3C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase Nat.Struct.Mol.Biol., 2024 Cited by DOI: 10.1038/s41594-024-01341-3PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.601 Å) |
Structure validation
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