8OWX
Crystal Structure of METTL6 bound to SAH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | tRNA N(3)-methylcytidine methyltransferase METTL6 | polymer | 275 | 32346.9 | 2 | UniProt (Q8TCB7) Pfam (PF08242) | Homo sapiens (human) | Methyltransferase-like protein 6,hMETTL6 |
| 2 | C, E (A, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 3 | D (A) | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 1 | Chemie (B3P) |
Sequence modifications
A, B: 1 - 271 (UniProt: Q8TCB7)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64693.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1051.2 | |
| All* | Total formula weight | 65744.9 |
