8OTR
SARS-CoV-2 nsp10-16 methyltransferase in complex with SAM analog BDH 33959089
Summary for 8OTR
Entry DOI | 10.2210/pdb8otr/pdb |
Related | 8BSD 8BZV 8C5M 8OSX 8OT0 |
Descriptor | 2'-O-methyltransferase nsp16, Non-structural protein 10, 1,2-ETHANEDIOL, ... (9 entities in total) |
Functional Keywords | viral protein, methyltransferase, complex, inhibitor, sars-cov-2 |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 2 |
Total formula weight | 51885.32 |
Authors | Kremling, V.,Sprenger, J.,Oberthuer, D. (deposition date: 2023-04-21, release date: 2023-05-24, Last modification date: 2024-06-19) |
Primary citation | Kremling, V.,Oberthuer, D.,Yefanov, O.,Galchenkova, M.,Middendorf, P.,Falke, S.,Fernandez Garcia, Y.,Ehrt, C.,Kiene, A.,Klopprogge, B.,Chapman, H.,Sprenger, J. Crystal structures of Tubercidin and Adenosine bound to the active site of the SARS-CoV-2 methyltransferase nsp10-16 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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