8OT0

SARS-CoV-2 nsp10-16 methyltransferase in complex with MTA and glycine

Summary for 8OT0

• Entry DOI: 10.2210/pdb8ot0/pdb
• Related: 8BSD 8BZV 8C5M 8OSX
• Descriptor: 2'-O-methyltransferase nsp16, Non-structural protein 10, 1,2-ETHANEDIOL, ... (8 entities in total)
• Functional Keywords: viral protein, methyltransferase, complex, inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 2
• Total formula weight: 51250.21

Authors

Kremling, V.,Sprenger, J.,Oberthuer, D.,Falke, S. (deposition date: 2023-04-20, release date: 2023-05-10, Last modification date: 2024-06-19)

• Primary citation: Kremling, V.,Sprenger, J.,Oberthuer, D.,Falke, S.,Yefanov, O.,Galchenkova, M.,Middendorf, P.,Garcia, Y.,Ehr, C.,Kiene, A.,Klopprogge, B.,Chapman, H.; Crystal structures of Tubercidin and Adenosine bound to the active site of the SARS-CoV-2 methyltransferase nsp10-16; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.21 Å)