8OSM
GTPASE HRAS IN COMPLEX WITH ZN-CYCLEN AT 200 MPA PRESSURE
Summary for 8OSM
Entry DOI | 10.2210/pdb8osm/pdb |
Related | 8OSN 8OSO |
Descriptor | GTPase HRas, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | g protein, signaling protein, hpmx, oncoprotein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 19571.86 |
Authors | Colloc'h, N.,Girard, E.,Prange, T.,Kalbitzer, H.R. (deposition date: 2023-04-19, release date: 2024-05-08, Last modification date: 2024-07-03) |
Primary citation | Girard, E.,Lopes, P.,Spoerner, M.,Dhaussy, A.C.,Prange, T.,Kalbitzer, H.R.,Colloc'h, N. High Pressure Promotes Binding of the Allosteric Inhibitor Zn 2+ -Cyclen in Crystals of Activated H-Ras. Chemistry, 30:e202400304-e202400304, 2024 Cited by PubMed: 38647362DOI: 10.1002/chem.202400304 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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