8OHT

Crystal structure of Beta-glucuronidase from Acidobacterium capsulatum in complex with competitive inhibitor derrived from siastatin B

This is a non-PDB format compatible entry.

Summary for 8OHT

• Entry DOI: 10.2210/pdb8oht/pdb
• Descriptor: beta-glucuronidase from Acidobacterium capsulatum, (3~{S},4~{S},5~{S},6~{R})-4,5,6-tris(oxidanyl)piperidine-3-carboxylic acid, SULFATE ION, ... (4 entities in total)
• Functional Keywords: inhibitor, complex, hydrolase
• Biological source: Acidobacterium capsulatum
• Total number of polymer chains: 1
• Total formula weight: 51087.78

Authors

Armstrong, Z.,Yurong, C.,Wu, L.,Overkleeft, H.S.,Davies, G.J. (deposition date: 2023-03-21, release date: 2024-01-10, Last modification date: 2024-01-24)

• Primary citation: Chen, Y.,van den Nieuwendijk, A.M.C.H.,Wu, L.,Moran, E.,Skoulikopoulou, F.,van Riet, V.,Overkleeft, H.S.,Davies, G.J.,Armstrong, Z.; Molecular Basis for Inhibition of Heparanases and beta-Glucuronidases by Siastatin B.; J.Am.Chem.Soc., 146:125-133, 2024; PubMed: 38118176; DOI: 10.1021/jacs.3c04162

Experimental method

X-RAY DIFFRACTION (1.05 Å)