8OGH
Truncated 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Mycobacterium tuberculosis with butylacetylphosphonate (BAP) bound
Summary for 8OGH
Entry DOI | 10.2210/pdb8ogh/pdb |
Descriptor | 1-deoxy-D-xylulose-5-phosphate synthase, [(S)-1-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl(phosphonooxy)phosphoryl]oxyethyl]-1,3-thiazol-3-ium-2-yl]-1-oxidanyl-ethyl]-butoxy-phosphinic acid, GLYCEROL, ... (7 entities in total) |
Functional Keywords | complex, inhibitor, thdp, mep-pathway, transferase |
Biological source | Mycobacterium tuberculosis H37Rv More |
Total number of polymer chains | 2 |
Total formula weight | 129448.61 |
Authors | Gawriljuk, O.V.,Oerlemans, R.,Groves, R.M. (deposition date: 2023-03-20, release date: 2023-05-10, Last modification date: 2023-10-25) |
Primary citation | Gawriljuk, V.O.,Oerlemans, R.,Gierse, R.M.,Jotwani, R.,Hirsch, A.K.H.,Groves, M.R. Structure of Mycobacterium tuberculosis 1-Deoxy-D-Xylulose 5-Phosphate Synthase in Complex with Butylacetylphosphonate Crystals, 13:-, 2023 Cited by DOI: 10.3390/cryst13050737PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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