8KC3
Cryo-EM structure of human C-terminally bound ATG9A-ATG2A-WIPI4 complex
Summary for 8KC3
| Entry DOI | 10.2210/pdb8kc3/pdb |
| EMDB information | 37091 |
| Descriptor | Autophagy-related protein 9A, WD repeat domain phosphoinositide-interacting protein 4, Autophagy-related protein 2 homolog A (3 entities in total) |
| Functional Keywords | lipid transfer, atg9a-atg2a-wipi4 complex, single particle cryo-em, autophagy, lipid transport-membrane protein complex, lipid transport/membrane protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 5 |
| Total formula weight | 536669.91 |
| Authors | Wang, Y.,Stjepanovic, G. (deposition date: 2023-08-05, release date: 2024-08-07, Last modification date: 2024-09-04) |
| Primary citation | Wang, Y.,Dahmane, S.,Ti, R.,Mai, X.,Zhu, L.,Carlson, L.A.,Stjepanovic, G. Structural basis for lipid transfer by the ATG2A-ATG9A complex. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 39174844DOI: 10.1038/s41594-024-01376-6 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (7 Å) |
Structure validation
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