8K1X

Biochemical and structural characterization of a multifunctional cytochrome P450 SpcN in staurosporine biosynthesis

Summary for 8K1X

• Entry DOI: 10.2210/pdb8k1x/pdb
• Descriptor: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, 13-(3-Amino-2,3,6-trideoxy-alpha-L-ribo-hexopyranosyl)-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one, ... (4 entities in total)
• Functional Keywords: cytochrome p450, biosynthetic protein
• Biological source: Streptomyces sanyensis
• Total number of polymer chains: 3
• Total formula weight: 150589.99

Authors

Xiao, F.,Dong, S.,Feng, Y.,Li, W. (deposition date: 2023-07-11, release date: 2024-10-16)

• Primary citation: Xiao, F.,Dong, S.,Feng, Y.,Li, W.; Molecular Basis for the P450-Catalyzed sp3 C-N Glycosidic Bond Formation in Staurosporine Biosynthesis.; Acs Catalysis, 14:14274-14284, 2024; DOI: 10.1021/acscatal.4c03875

Experimental method

X-RAY DIFFRACTION (2.27 Å)