8K1X
Biochemical and structural characterization of a multifunctional cytochrome P450 SpcN in staurosporine biosynthesis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Cytochrome P450 | polymer | 440 | 48699.2 | 3 | UniProt (W5R4Y8) Pfam (PF00067) | Streptomyces sanyensis | |
| 2 | D, G, K (A, B, C) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 3 | Chemie (HEM) | |||
| 3 | E, F, H, I, J... (A, B, C) | 13-(3-Amino-2,3,6-trideoxy-alpha-L-ribo-hexopyranosyl)-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one | non-polymer | 440.5 | 6 | Chemie (VI4) | |||
| 4 | M, N, O (A, B, C) | water | water | 18.0 | 231 | Chemie (HOH) |
Sequence modifications
A, B, C: 27 - 416 (UniProt: W5R4Y8)
| PDB | External Database | Details |
|---|---|---|
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Met 1 | - | expression tag |
| Asn 2 | - | expression tag |
| Val 3 | - | expression tag |
| Thr 4 | - | expression tag |
| Thr 5 | - | expression tag |
| Lys 6 | - | expression tag |
| Thr 7 | - | expression tag |
| Gly 8 | - | expression tag |
| Leu 9 | - | expression tag |
| Ala 10 | - | expression tag |
| Glu 11 | - | expression tag |
| Ala 12 | - | expression tag |
| Pro 13 | - | expression tag |
| Glu 14 | - | expression tag |
| Ala 15 | - | expression tag |
| His 16 | - | expression tag |
| Met 17 | - | expression tag |
| Pro 18 | - | expression tag |
| Thr 19 | - | expression tag |
| Asp 20 | - | expression tag |
| Pro 21 | - | expression tag |
| Gly 22 | - | expression tag |
| Pro 23 | - | expression tag |
| Phe 24 | - | expression tag |
| Asp 25 | - | expression tag |
| Cys 26 | - | expression tag |
| Leu 417 | - | expression tag |
| Glu 418 | - | expression tag |
| His 419 | - | expression tag |
| His 420 | - | expression tag |
| His 421 | - | expression tag |
| His 422 | - | expression tag |
| His 423 | - | expression tag |
| His 424 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 146097.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 4492.4 | |
| All* | Total formula weight | 150590.0 |
