8JY8
Structure of TbAQP2 in complex with anti-trypanosomatid drug pentamidine
Summary for 8JY8
Entry DOI | 10.2210/pdb8jy8/pdb |
EMDB information | 36723 |
Descriptor | Aquaglyceroporin 2, 1,5-BIS(4-AMIDINOPHENOXY)PENTANE (2 entities in total) |
Functional Keywords | aquaporin, membrane protein |
Biological source | Trypanosoma brucei brucei |
Total number of polymer chains | 4 |
Total formula weight | 135820.26 |
Authors | |
Primary citation | Chen, W.,Zou, R.,Mei, Y.,Li, J.,Xuan, Y.,Cui, B.,Zou, J.,Wang, J.,Lin, S.,Zhang, Z.,Wang, C. Structural insights into drug transport by an aquaglyceroporin. Nat Commun, 15:3985-3985, 2024 Cited by PubMed: 38734677DOI: 10.1038/s41467-024-48445-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.45 Å) |
Structure validation
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