8JVA

Cryo-EM structure of the N-terminal domain of Omicron BA.1 in complex with nanobody N235 and S2L20 Fab

Summary for 8JVA

• Entry DOI: 10.2210/pdb8jva/pdb
• EMDB information: 36672
• Descriptor: nanobody N235, S2L20 light chain, S2L20 heavy chain, ... (5 entities in total)
• Functional Keywords: complex, viral protein/immune system, viral protein-immune system complex
• Biological source: Vicugna pacos; More
• Total number of polymer chains: 4
• Total formula weight: 127212.58

Authors

Liu, B.,Liu, H.H.,Han, P.,Qi, J.X. (deposition date: 2023-06-28, release date: 2024-05-22)

• Primary citation: Liu, B.,Liu, H.,Han, P.,Wang, X.,Wang, C.,Yan, X.,Lei, W.,Xu, K.,Zhou, J.,Qi, J.,Fan, R.,Wu, G.,Tian, W.X.,Gao, G.F.,Wang, Q.; Enhanced potency of an IgM-like nanobody targeting conserved epitope in SARS-CoV-2 spike N-terminal domain.; Signal Transduct Target Ther, 9:131-131, 2024; PubMed: 38740785; DOI: 10.1038/s41392-024-01847-8

Experimental method

ELECTRON MICROSCOPY (2.81 Å)