8JVA
Cryo-EM structure of the N-terminal domain of Omicron BA.1 in complex with nanobody N235 and S2L20 Fab
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | D | nanobody N235 | polymer | 126 | 13970.4 | 1 | Vicugna pacos | ||
2 | A | S2L20 light chain | polymer | 236 | 26018.0 | 1 | Homo sapiens (human) | ||
3 | B | S2L20 heavy chain | polymer | 473 | 52041.5 | 1 | Homo sapiens (human) | ||
4 | F | Spike protein S2' | polymer | 300 | 34076.6 | 1 | UniProt (P0DTC2) Pfam (PF16451) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | |
5 | F | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) |
Sequence modifications
F: 1 - 303 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Val 67 | Ala 67 | variant |
- | His 69 | deletion |
- | Val 70 | deletion |
Ile 95 | Thr 95 | variant |
- | Gly 142 | deletion |
- | Val 143 | deletion |
- | Tyr 144 | deletion |
Asp 145 | Tyr 145 | variant |
- | Asn 211 | deletion |
Ile 210 | Leu 212 | variant |
Glu 212 | - | insertion |
Pro 213 | - | insertion |
Glu 214 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 126106.5 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1106.0 | |
All* | Total formula weight | 127212.6 |