8JPX
Cryo-EM structure of PfAgo-guide DNA-target DNA complex
Summary for 8JPX
Entry DOI | 10.2210/pdb8jpx/pdb |
EMDB information | 36489 |
Descriptor | Protein argonaute, Guide DNA, Target DNA, ... (5 entities in total) |
Functional Keywords | nuclease, gene regulation |
Biological source | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) More |
Total number of polymer chains | 8 |
Total formula weight | 205552.00 |
Authors | Zhuang, L. (deposition date: 2023-06-13, release date: 2024-01-31, Last modification date: 2024-05-01) |
Primary citation | Wang, L.,Chen, W.,Zhang, C.,Xie, X.,Huang, F.,Chen, M.,Mao, W.,Yu, N.,Wei, Q.,Ma, L.,Li, Z. Molecular mechanism for target recognition, dimerization, and activation of Pyrococcus furiosus Argonaute. Mol.Cell, 84:675-686.e4, 2024 Cited by PubMed: 38295801DOI: 10.1016/j.molcel.2024.01.004 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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