8JJE

RBD of SARS-CoV2 spike protein with ACE2 decoy

Summary for 8JJE

Entry DOI	10.2210/pdb8jje/pdb
EMDB information	36345
Descriptor	Angiotensin-converting enzyme 2, Spike glycoprotein, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
Functional Keywords	sars-cov2, spike protein, ace2, ace2 decoy, viral protein, viral protein-protein binding complex, viral protein/protein binding
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	215458.99
Authors	Kishikawa, J.,Hirose, M.,Kato, T.,Okamoto, T. (deposition date: 2023-05-30, release date: 2023-12-27)
Primary citation	Urano, E.,Itoh, Y.,Suzuki, T.,Sasaki, T.,Kishikawa, J.I.,Akamatsu, K.,Higuchi, Y.,Sakai, Y.,Okamura, T.,Mitoma, S.,Sugihara, F.,Takada, A.,Kimura, M.,Nakao, S.,Hirose, M.,Sasaki, T.,Koketsu, R.,Tsuji, S.,Yanagida, S.,Shioda, T.,Hara, E.,Matoba, S.,Matsuura, Y.,Kanda, Y.,Arase, H.,Okada, M.,Takagi, J.,Kato, T.,Hoshino, A.,Yasutomi, Y.,Saito, A.,Okamoto, T. An inhaled ACE2 decoy confers protection against SARS-CoV-2 infection in preclinical models. Sci Transl Med, 15:eadi2623-eadi2623, 2023 Cited by PubMed: 37647387 DOI: 10.1126/scitranslmed.adi2623 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.4 Å)

Structure validation