8JJE
RBD of SARS-CoV2 spike protein with ACE2 decoy
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Angiotensin-converting enzyme 2 | polymer | 639 | 73198.1 | 1 | UniProt (Q9BYF1) Pfam (PF01401) | Homo sapiens (human) | Angiotensin-converting enzyme homolog,ACEH,Angiotensin-converting enzyme-related carboxypeptidase,ACE-related carboxypeptidase,Metalloprotease MPROT15 |
| 2 | B (B) | Spike glycoprotein | polymer | 1251 | 138621.2 | 1 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | S glycoprotein,E2,Peplomer protein |
| 3 | C (E) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G10756ZZ) | |||
| 4 | D, E (F, G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 5 | F (H) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 6 | G (I) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 7 | H (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 8 | I (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 9 | J (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 10 | K (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 1 - 615 (UniProt: Q9BYF1)
B: 14 - 1211 (UniProt: P0DTC2)
B: 1212 - 1262 (PDB: 8JJE)
| PDB | External Database | Details |
|---|---|---|
| Val 25 | Ala 25 | engineered mutation |
| Asn 31 | Lys 31 | engineered mutation |
| Lys 35 | Glu 35 | engineered mutation |
| Gln 92 | Thr 92 | engineered mutation |
| Cys 128 | Ser 128 | engineered mutation |
| Cys 343 | Val 343 | engineered mutation |
| Glu 616 | - | expression tag |
| Phe 617 | - | expression tag |
| Ser 618 | - | expression tag |
| Gly 619 | - | expression tag |
| Gly 620 | - | expression tag |
| Gly 621 | - | expression tag |
| Gly 622 | - | expression tag |
| Ser 623 | - | expression tag |
| Gly 624 | - | expression tag |
| Gly 625 | - | expression tag |
| Gly 626 | - | expression tag |
| Gly 627 | - | expression tag |
| Ser 628 | - | expression tag |
| Gly 629 | - | expression tag |
| Gly 630 | - | expression tag |
| Gly 631 | - | expression tag |
| Gly 632 | - | expression tag |
| Ser 633 | - | expression tag |
| His 634 | - | expression tag |
| His 635 | - | expression tag |
| His 636 | - | expression tag |
| His 637 | - | expression tag |
| His 638 | - | expression tag |
| His 639 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 12 | - | expression tag |
| Glu 13 | - | expression tag |
| Gly 682 | Arg 682 | engineered mutation |
| Ser 683 | Arg 683 | engineered mutation |
| Gly 685 | Arg 685 | engineered mutation |
| Pro 986 | Lys 986 | engineered mutation |
| Pro 987 | Val 987 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 211819.3 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 3257.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 382.7 | |
| All* | Total formula weight | 215459.0 |
