8JJE
RBD of SARS-CoV2 spike protein with ACE2 decoy
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Angiotensin-converting enzyme 2 | polymer | 639 | 73198.1 | 1 | UniProt (Q9BYF1) Pfam (PF01401) In PDB | Homo sapiens (human) | Angiotensin-converting enzyme homolog,ACEH,Angiotensin-converting enzyme-related carboxypeptidase,ACE-related carboxypeptidase,Metalloprotease MPROT15 |
2 | B | Spike glycoprotein | polymer | 1251 | 138621.2 | 1 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | S glycoprotein,E2,Peplomer protein |
3 | E | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G10756ZZ) | |||
4 | F, G | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
5 | H | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
6 | I | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
7 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
8 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
9 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
10 | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 1 - 615 (UniProt: Q9BYF1)
B: 14 - 1211 (UniProt: P0DTC2)
B: 1212 - 1262 (PDB: 8JJE)
PDB | External Database | Details |
---|---|---|
Val 25 | Ala 25 | engineered mutation |
Asn 31 | Lys 31 | engineered mutation |
Lys 35 | Glu 35 | engineered mutation |
Gln 92 | Thr 92 | engineered mutation |
Cys 128 | Ser 128 | engineered mutation |
Cys 343 | Val 343 | engineered mutation |
Glu 616 | - | expression tag |
Phe 617 | - | expression tag |
Ser 618 | - | expression tag |
Gly 619 | - | expression tag |
Gly 620 | - | expression tag |
Gly 621 | - | expression tag |
Gly 622 | - | expression tag |
Ser 623 | - | expression tag |
Gly 624 | - | expression tag |
Gly 625 | - | expression tag |
Gly 626 | - | expression tag |
Gly 627 | - | expression tag |
Ser 628 | - | expression tag |
Gly 629 | - | expression tag |
Gly 630 | - | expression tag |
Gly 631 | - | expression tag |
Gly 632 | - | expression tag |
Ser 633 | - | expression tag |
His 634 | - | expression tag |
His 635 | - | expression tag |
His 636 | - | expression tag |
His 637 | - | expression tag |
His 638 | - | expression tag |
His 639 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Leu 12 | - | expression tag |
Glu 13 | - | expression tag |
Gly 682 | Arg 682 | engineered mutation |
Ser 683 | Arg 683 | engineered mutation |
Gly 685 | Arg 685 | engineered mutation |
Pro 986 | Lys 986 | engineered mutation |
Pro 987 | Val 987 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 211819.3 | |
Branched | Number of molecules | 5 |
Total formula weight | 3257.0 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 382.7 | |
All* | Total formula weight | 215459.0 |