8JH1
Crystal Structure of the Csm6 Y161A mutant from Thermus thermophilus HB8 in complex with cyclic-tetraadenylate (cA4)
Summary for 8JH1
Entry DOI | 10.2210/pdb8jh1/pdb |
Descriptor | CRISPR system endoribonuclease Csm6, RNA (5'-R(P*AP*AP*AP*A)-3') (3 entities in total) |
Functional Keywords | thermus thermophilus hb8, csm6, endoribonuclease, cyclic-tetraadenylate (ca4), hydrolase |
Biological source | Thermus thermophilus HB8 More |
Total number of polymer chains | 3 |
Total formula weight | 103199.19 |
Authors | |
Primary citation | Du, L.,Zhu, Q.,Lin, Z. Molecular mechanism of allosteric activation of the CRISPR ribonuclease Csm6 by cyclic tetra-adenylate. Embo J., 43:304-315, 2024 Cited by PubMed: 38177499DOI: 10.1038/s44318-023-00017-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.89 Å) |
Structure validation
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