8JH1
Crystal Structure of the Csm6 Y161A mutant from Thermus thermophilus HB8 in complex with cyclic-tetraadenylate (cA4)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | CRISPR system endoribonuclease Csm6 | polymer | 463 | 50963.7 | 2 | UniProt (Q53W17) Pfam (PF22205) Pfam (PF09670) | Thermus thermophilus HB8 | CRISPR type III-A associated protein Csm6,TtCsm6 |
| 2 | C (C) | RNA (5'-R(P*AP*AP*AP*A)-3') | polymer | 4 | 1271.9 | 1 | synthetic construct | ||
| 3 | D, E (A, B) | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 464 (UniProt: Q53W17)
| PDB | External Database | Details |
|---|---|---|
| Ala 161 | Tyr 161 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 103199.2 | |
| All* | Total formula weight | 103199.2 |
