8J86
Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in a DNA binding form
Summary for 8J86
Entry DOI | 10.2210/pdb8j86/pdb |
Related | 8HDZ 8HOY 8HPA |
EMDB information | 36061 |
Descriptor | DNA polymerase, E4R, DNA polymerase processivity factor component A20, ... (6 entities in total) |
Functional Keywords | monkeypox virus, dna replication holoenzyme, dna replication machinery, dna polymerase, b-family dna polymerase, uracil-dna glycosylase, mpxv, orthopoxvirus, poxviridae, dna processivity factor, dna, viral protein |
Biological source | Monkeypox virus More |
Total number of polymer chains | 5 |
Total formula weight | 216293.33 |
Authors | |
Primary citation | Xu, Y.,Wu, Y.,Wu, X.,Zhang, Y.,Yang, Y.,Li, D.,Yang, B.,Gao, K.,Zhang, Z.,Dong, C. Structural basis of human mpox viral DNA replication inhibition by brincidofovir and cidofovir. Int.J.Biol.Macromol., 270:132231-132231, 2024 Cited by PubMed: 38735603DOI: 10.1016/j.ijbiomac.2024.132231 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.22 Å) |
Structure validation
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