8IZT

Crystal structure of the N-terminal domain (residues 1-121) of MPXV A7

Summary for 8IZT

• Entry DOI: 10.2210/pdb8izt/pdb
• Descriptor: Virion morphogenesis protein OPG132, ZINC ION (3 entities in total)
• Functional Keywords: mpxv, a7, n-terminus, viral protein
• Biological source: Monkeypox virus
• Total number of polymer chains: 1
• Total formula weight: 14411.35

Authors

Ni, X.C.,Lei, J. (deposition date: 2023-04-08, release date: 2024-04-17, Last modification date: 2024-05-22)

Primary citation

Ni, X.,Wang, K.,Han, Y.,Lei, J.
Structural analysis of conformational changes in the mpox virus A7 protein.
Virol Sin, 39:331-334, 2024

PubMed Abstract: • Phospholipid-binding abilities of mpox virus A7 protein and its truncations are investigated. • The structures of the N-terminal truncations of A7 protein (A7N and A7N) are determined. • Conformational changes of the conserved linking helix in A7 are illustrated. • A structural model of the full-length A7 protein is proposed.

PubMed: 38159644
DOI: 10.1016/j.virs.2023.12.006

Experimental method

X-RAY DIFFRACTION (1.74 Å)