8I96

Cryo-EM structure of TLR7/TH-407b complex

Summary for 8I96

• Entry DOI: 10.2210/pdb8i96/pdb
• EMDB information: 35258
• Descriptor: Toll-like receptor 7, (1S,3R)-5-[4-(8-nitroquinolin-5-yl)piperazin-1-yl]carbonyladamantan-2-one (2 entities in total)
• Functional Keywords: tlr7, antagonist, immune system
• Biological source: Macaca mulatta (Rhesus monkey)
• Total number of polymer chains: 2
• Total formula weight: 190360.16

Authors

Zhang, Z. (deposition date: 2023-02-06, release date: 2024-08-14, Last modification date: 2025-06-25)

• Primary citation: Zhang, Z.,Yin, H.,Shimizu, T.; Cryo-EM structure of TLR7/TH-407b complex; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.2 Å)