8HYK
CD-NTase EfCdnE in complex with intermediate pppU[2'-5']p
Summary for 8HYK
Entry DOI | 10.2210/pdb8hyk/pdb |
Descriptor | EfCdnE, [[(2R,3R,4R,5R)-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | cd-ntase, cgas, cyclic dinucleotide, transferase |
Biological source | Enterococcus faecalis EnGen0062 |
Total number of polymer chains | 1 |
Total formula weight | 36339.89 |
Authors | Ko, T.-P.,Wang, Y.-C.,Yang, C.-S.,Hou, M.-H.,Chen, Y. (deposition date: 2023-01-06, release date: 2023-07-05, Last modification date: 2023-09-13) |
Primary citation | Yang, C.S.,Ko, T.P.,Chen, C.J.,Hou, M.H.,Wang, Y.C.,Chen, Y. Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases. Nat Commun, 14:5078-5078, 2023 Cited by PubMed: 37604815DOI: 10.1038/s41467-023-40787-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.021 Å) |
Structure validation
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