8HYK

CD-NTase EfCdnE in complex with intermediate pppU[2'-5']p

Summary for 8HYK

Entry DOI	10.2210/pdb8hyk/pdb
Descriptor	EfCdnE, [[(2R,3R,4R,5R)-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	cd-ntase, cgas, cyclic dinucleotide, transferase
Biological source	Enterococcus faecalis EnGen0062
Total number of polymer chains	1
Total formula weight	36339.89
Authors	Ko, T.-P.,Wang, Y.-C.,Yang, C.-S.,Hou, M.-H.,Chen, Y. (deposition date: 2023-01-06, release date: 2023-07-05, Last modification date: 2023-09-13)
Primary citation	Yang, C.S.,Ko, T.P.,Chen, C.J.,Hou, M.H.,Wang, Y.C.,Chen, Y. Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases. Nat Commun, 14:5078-5078, 2023 Cited by PubMed: 37604815 DOI: 10.1038/s41467-023-40787-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.021 Å)

Structure validation