8HVR
Cryo-EM structure of AfsR-dependent transcription activation complex with afsS promoter
Summary for 8HVR
Entry DOI | 10.2210/pdb8hvr/pdb |
EMDB information | 35047 |
Descriptor | DNA-directed RNA polymerase subunit alpha, DNA (65-MER), MAGNESIUM ION, ... (12 entities in total) |
Functional Keywords | rna polymerase, sarp regulator, gene regulation, transcription |
Biological source | Streptomyces coelicolor A3(2) More |
Total number of polymer chains | 13 |
Total formula weight | 587733.18 |
Authors | |
Primary citation | Wang, Y.,Yang, X.,Yu, F.,Deng, Z.,Lin, S.,Zheng, J. Structural and functional characterization of AfsR, an SARP family transcriptional activator of antibiotic biosynthesis in Streptomyces. Plos Biol., 22:e3002528-e3002528, 2024 Cited by PubMed: 38427710DOI: 10.1371/journal.pbio.3002528 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.35 Å) |
Structure validation
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