8HUE

Crystal structure of FGF2-M2 mutant - D28E/C78I/C96I/S137P

Summary for 8HUE

• Entry DOI: 10.2210/pdb8hue/pdb
• Related PRD ID: PRD_900013
• Descriptor: Fibroblast growth factor 2, 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose (3 entities in total)
• Functional Keywords: basic fibroblast growth factor, fibroblast growth factor 2, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 51799.04

Authors

Jung, Y.E.,Cha, S.S.,An, Y.J. (deposition date: 2022-12-23, release date: 2024-06-26, Last modification date: 2024-10-16)

• Primary citation: An, Y.J.,Jung, Y.E.,Lee, K.W.,Kaushal, P.,Ko, I.Y.,Shin, S.M.,Ji, S.,Yu, W.,Lee, C.,Lee, W.K.,Cha, K.,Lee, J.H.,Cha, S.S.,Yim, H.S.; Structural and biochemical investigation into stable FGF2 mutants with novel mutation sites and hydrophobic replacements for surface-exposed cysteines.; Plos One, 19:e0307499-e0307499, 2024; PubMed: 39236042; DOI: 10.1371/journal.pone.0307499

Experimental method

X-RAY DIFFRACTION (1.48 Å)