8HUE
Crystal structure of FGF2-M2 mutant - D28E/C78I/C96I/S137P
Summary for 8HUE
Entry DOI | 10.2210/pdb8hue/pdb |
Related PRD ID | PRD_900013 |
Descriptor | Fibroblast growth factor 2, 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose (3 entities in total) |
Functional Keywords | basic fibroblast growth factor, fibroblast growth factor 2, signaling protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 3 |
Total formula weight | 51799.04 |
Authors | Jung, Y.E.,Cha, S.S.,An, Y.J. (deposition date: 2022-12-23, release date: 2024-06-26, Last modification date: 2024-10-16) |
Primary citation | An, Y.J.,Jung, Y.E.,Lee, K.W.,Kaushal, P.,Ko, I.Y.,Shin, S.M.,Ji, S.,Yu, W.,Lee, C.,Lee, W.K.,Cha, K.,Lee, J.H.,Cha, S.S.,Yim, H.S. Structural and biochemical investigation into stable FGF2 mutants with novel mutation sites and hydrophobic replacements for surface-exposed cysteines. Plos One, 19:e0307499-e0307499, 2024 Cited by PubMed: 39236042DOI: 10.1371/journal.pone.0307499 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.48 Å) |
Structure validation
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