8HUE

Crystal structure of FGF2-M2 mutant - D28E/C78I/C96I/S137P

8HUE の概要

• エントリーDOI: 10.2210/pdb8hue/pdb
• 関連するBIRD辞書のPRD_ID: PRD_900013
• 分子名称: Fibroblast growth factor 2, 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose (3 entities in total)
• 機能のキーワード: basic fibroblast growth factor, fibroblast growth factor 2, signaling protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 51799.04

構造登録者

Jung, Y.E.,Cha, S.S.,An, Y.J. (登録日: 2022-12-23, 公開日: 2024-06-26, 最終更新日: 2024-10-16)

• 主引用文献: An, Y.J.,Jung, Y.E.,Lee, K.W.,Kaushal, P.,Ko, I.Y.,Shin, S.M.,Ji, S.,Yu, W.,Lee, C.,Lee, W.K.,Cha, K.,Lee, J.H.,Cha, S.S.,Yim, H.S.; Structural and biochemical investigation into stable FGF2 mutants with novel mutation sites and hydrophobic replacements for surface-exposed cysteines.; Plos One, 19:e0307499-e0307499, 2024; PubMed: 39236042; DOI: 10.1371/journal.pone.0307499

実験手法

X-RAY DIFFRACTION (1.48 Å)