8HNN
Structure of CXCR3 complexed with antagonist SCH546738
Summary for 8HNN
Entry DOI | 10.2210/pdb8hnn/pdb |
EMDB information | 34917 |
Descriptor | Nb6, Soluble cytochrome b562,C-X-C chemokine receptor type 3,Kappa-type opioid receptor, 3-azanyl-6-chloranyl-5-[(3S)-4-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-3-ethyl-piperazin-1-yl]pyrazine-2-carboxamide, ... (4 entities in total) |
Functional Keywords | g protein coupled receptor, chemokine receptor, cxcr3, sch546738, complex, signaling protein |
Biological source | Lama glama More |
Total number of polymer chains | 2 |
Total formula weight | 75872.06 |
Authors | Jiao, H.Z.,Hu, H.L. (deposition date: 2022-12-08, release date: 2023-11-29, Last modification date: 2024-10-09) |
Primary citation | Jiao, H.,Pang, B.,Liu, A.,Chen, Q.,Pan, Q.,Wang, X.,Xu, Y.,Chiang, Y.C.,Ren, R.,Hu, H. Structural insights into the activation and inhibition of CXC chemokine receptor 3. Nat.Struct.Mol.Biol., 31:610-620, 2024 Cited by PubMed: 38177682DOI: 10.1038/s41594-023-01175-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
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