8HMT

The complex of ACK1 with the inhibitor 2-142

Summary for 8HMT

• Entry DOI: 10.2210/pdb8hmt/pdb
• Descriptor: Activated CDC42 kinase 1, 6-(2-bromophenyl)-2-[[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino]-8-[[(2S)-oxolan-2-yl]methyl]pyrido[2,3-d]pyrimidin-7-one (2 entities in total)
• Functional Keywords: inhibitor, complex, ack1, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 127258.47

Authors

Zhu, S.,Xiaoyun, X.Y. (deposition date: 2022-12-05, release date: 2023-12-13)

• Primary citation: Zhu, S.,Xiaoyun, X.Y.; The complex of ACK1 with the inhibitor 2-142; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.17 Å)