8HMT

The complex of ACK1 with the inhibitor 2-142

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Activated CDC42 kinase 1	polymer	273	31225.1	4	UniProt (Q07912) Pfam (PF07714)	Homo sapiens (human)	ACK-1,Tyrosine kinase non-receptor protein 2
2	E, F, G, H (A, B, C, D)	6-(2-bromophenyl)-2-[[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino]-8-[[(2S)-oxolan-2-yl]methyl]pyrido[2,3-d]pyrimidin-7-one	non-polymer		589.5	4	Chemie (LWX)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	124900.4
Non-Polymers*	Number of molecules	4
	Total formula weight	2358.1
All*	Total formula weight	127258.5

*Water molecules are not included.