8HK7
Structure of PKD2-F604P (Polycystin-2, TRPP2) with ML-SA1
Summary for 8HK7
Entry DOI | 10.2210/pdb8hk7/pdb |
EMDB information | 34848 |
Descriptor | Polycystin-2, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 268263.57 |
Authors | |
Primary citation | Wang, Z.,Chen, M.,Su, Q.,Morais, T.D.C.,Wang, Y.,Nazginov, E.,Pillai, A.R.,Qian, F.,Shi, Y.,Yu, Y. Molecular and structural basis of the dual regulation of the polycystin-2 ion channel by small-molecule ligands. Proc.Natl.Acad.Sci.USA, 121:e2316230121-e2316230121, 2024 Cited by PubMed: 38483987DOI: 10.1073/pnas.2316230121 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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