8HFF
Cryo-EM structure of human norepinephrine transporter NET in the presence of norepinephrine in an inward-open state at resolution of 2.9 angstrom.
Summary for 8HFF
Entry DOI | 10.2210/pdb8hff/pdb |
Related | 8HFE |
EMDB information | 34718 34719 |
Descriptor | Sodium-dependent noradrenaline transporter, L-NOREPINEPHRINE (3 entities in total) |
Functional Keywords | norepinephrine transporter, net, slc6a2, norepinephrine, dopamine, neurotransmitter, desipramine, bupropion, antidepressant., transport protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 69724.90 |
Authors | |
Primary citation | Tan, J.,Xiao, Y.,Kong, F.,Lei, J.,Yuan, Y.,Yan, C. Molecular basis for the reuptake and inhibition of human norepinephrine transporter To Be Published, |
Experimental method | ELECTRON MICROSCOPY (2.86 Å) |
Structure validation
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