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8HFF

Cryo-EM structure of human norepinephrine transporter NET in the presence of norepinephrine in an inward-open state at resolution of 2.9 angstrom.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Sodium-dependent noradrenaline transporterpolymer61769386.51UniProt (P23975)
Pfam (PF00209)
Homo sapiens (human)Norepinephrine transporter,NET,Solute carrier family 6 member 2
2B, C
(A)
L-NOREPINEPHRINEnon-polymer169.22Chemie (LNR)
3D
(A)
waterwater18.02Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight69386.5
Non-Polymers*Number of molecules2
Total formula weight338.4
All*Total formula weight69724.9
*Water molecules are not included.

238582

PDB entries from 2025-07-09

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