8HCX
Cryo-EM structure of Endothelin1-bound ETBR-Gq complex
Summary for 8HCX
Entry DOI | 10.2210/pdb8hcx/pdb |
EMDB information | 34667 |
Descriptor | Guanine nucleotide-binding protein G(q) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Endothelin receptor type B,Oplophorus-luciferin 2-monooxygenase catalytic subunit chimera, ... (6 entities in total) |
Functional Keywords | et1, etar, gq, scfv16, membrane protein |
Biological source | Homo sapiens More |
Total number of polymer chains | 6 |
Total formula weight | 177745.16 |
Authors | |
Primary citation | Ji, Y.,Duan, J.,Yuan, Q.,He, X.,Yang, G.,Zhu, S.,Wu, K.,Hu, W.,Gao, T.,Cheng, X.,Jiang, H.,Eric Xu, H.,Jiang, Y. Structural basis of peptide recognition and activation of endothelin receptors. Nat Commun, 14:1268-1268, 2023 Cited by PubMed: 36882417DOI: 10.1038/s41467-023-36998-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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