8HCR

Cryo-EM structure of the Mycobacterium tuberculosis cytochrome bcc:aa3 supercomplex and a novel inhibitor targeting subunit cytochrome cI

8HCR の概要

• エントリーDOI: 10.2210/pdb8hcr/pdb
• EMDBエントリー: 34664
• 分子名称: Cytochrome bc1 complex Rieske iron-sulfur subunit, FE2/S2 (INORGANIC) CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, ... (13 entities in total)
• 機能のキーワード: cytochrome bcc:aa3 oxidase, mycobacterium tuberculosis, oxidoreductase
• 由来する生物種: Mycobacterium tuberculosis variant bovis BCG; 詳細
• タンパク質・核酸の鎖数: 18
• 化学式量合計: 620764.09

構造登録者

Mathiyazakan, V.,Gruber, G. (登録日: 2022-11-02, 公開日: 2023-05-03, 最終更新日: 2023-09-13)

• 主引用文献: Mathiyazakan, V.,Wong, C.F.,Harikishore, A.,Pethe, K.,Gruber, G.; Cryo-Electron Microscopy Structure of the Mycobacterium tuberculosi s Cytochrome bcc : aa 3 Supercomplex and a Novel Inhibitor Targeting Subunit Cytochrome c I.; Antimicrob.Agents Chemother., 67:e0153122-e0153122, 2023; PubMed: 37158740; DOI: 10.1128/aac.01531-22

実験手法

ELECTRON MICROSCOPY